|2 news drugs recently approved show to offer benefits
Recently the FDA approved two drugs that may offer benefits for patients with diabetic peripheral neuropathy.
Pregabaline from Pfizer marketed under the name of Lyrica® works by a newly discovered mechanism of action, blocking a receptor on over-firing nerve cells and reducing the symptoms of nerve pain. the safety and efficacy of pregabaline was establish in at least six doubled blind, placebo clinical trials. Summing up around 50% of patients taking the drug show improvements in contrast only 18% of those who took placebo. Side effects from drug therapy were few but it may appear dizziness, sleepiness, dry mouth, peripheral edema, blurred vision, weight gain, and difficulty with concentration. Is particularly suitable for patients who fail other therapies.
Duloxetine from Lilly and marketed under the name of Cymbalta® was approved previously as an antidepressant drug, targets serotonin and norepinepherine, both believed to play were proven in two randomized studies of 1074 patients. In this trials 58% of patients reported improvements compared to 34% in the placebo group. Side effect were few but included nausea, dry mouth, constipation and diarrhea some patients experienced dizziness and hot flashes.
|If you are experiencing pain from peripheral diabetic neuropathy ask your doctor about the possibility of these two drugs.